Alfredo Butternut Squash Pasta

Featured in: Dinner Winners

Experience creamy comfort in this pasta bake featuring roasted butternut squash and a rich Alfredo sauce. Tender pasta and sweet squash pieces are layered and coated in a smooth, cheesy blend of milk, cream, and Parmesan, then topped with mozzarella for that perfect golden, bubbling finish. Simple to prepare and ideal for cozy dinners or entertaining, it combines classic Italian-American flavors with nourishing vegetarian ingredients. Serve hot, garnished with fresh parsley for added brightness, and enjoy a hearty, satisfying dish everyone will love.

Updated on Thu, 23 Oct 2025 14:20:56 GMT
Golden Alfredo Butternut Squash Pasta Bake awaits, bubbly cheese topping a creamy dream. Save
Golden Alfredo Butternut Squash Pasta Bake awaits, bubbly cheese topping a creamy dream. | tastybattle.com

This Alfredo Butternut Squash Pasta Bake is the kind of nourishing crowd-pleasing main dish you want for cool evenings or laid-back get-togethers. It is a bubbling cheese-topped pasta casserole packed with roasted butternut squash and drenched in luscious homemade Alfredo sauce. Every forkful delivers creamy richness and cozy comfort making it a favorite for both vegetarians and anyone craving a hearty meal.

When I make this for my family we always end up crowded around the table a little early just to scoop the first cheesy bite. It is a go-to for nights when we need both comfort and something special.

Ingredients

  • Penne or rigatoni pasta: Look for brands made with durum wheat for ideal texture that holds up to baking
  • Butternut squash: Choose a squash that feels heavy for its size with smooth matte skin for natural sweetness
  • Yellow onion: Adds sweetness and depth once sautéed until soft and golden
  • Garlic: Use fresh cloves for boldness that cuts through the rich sauce
  • Olive oil: A light drizzle brings out the squash’s natural flavors during roasting
  • Unsalted butter: Gives the Alfredo sauce its luxurious base and helps build the classic creamy texture
  • All-purpose flour: This is your thickener Be sure it’s fresh so your sauce cooks up smooth
  • Whole milk and heavy cream: A combo that turns out extra velvety sauce You can substitute part of the milk with half-and-half for a lighter feel
  • Freshly grated Parmesan cheese: Freshly grated absolutely melts better and tastes deeper Avoid pre-shredded
  • Salt pepper and nutmeg: These season simply and bring warmth Choose freshly grated nutmeg if you can
  • Shredded mozzarella cheese and more Parmesan: For a golden cheesy lid that gives perfect bubbly comfort
  • Chopped fresh parsley: For brightness and color on serving I love using flat leaf parsley

Instructions

Preheat and Prep the Baking Dish:
Set your oven to a hot 200 Celsius so the squash and cheese bake evenly Grease your baking dish well so nothing sticks
Roast the Butternut Squash:
Toss squash cubes in olive oil with just a sprinkle of salt and pepper Spread out so they roast not steam and stir halfway for perfect caramelization
Cook the Pasta:
Boil your pasta in salty water but pull it out a few minutes early That way it will not overcook in the oven and will soak up the sauce just right Drain and set aside
Sauté Aromatics for the Sauce:
Melt butter in your saucepan then soften the onions gently till they are golden and nearly melting in the pan Add garlic just until fragrant for background warmth
Build the Alfredo Sauce:
Stir in flour and let it cook for a minute to lose any raw taste Slowly whisk in milk then cream letting the mixture thicken until glossy Stir constantly so it stays lump-free
Finish the Sauce:
Off the heat fold in Parmesan salt pepper and nutmeg Keep stirring until every bit of cheese melts into a silky sauce with just enough thickness
Combine All Components:
In a large mixing bowl start with hot pasta add roasted squash then Alfredo sauce Toss gently so every piece is generously coated without breaking
Assemble and Top:
Pour the mixture into your greased baking dish Shake to settle everything even Sprinkle on mozzarella and extra Parmesan for a golden finish
Bake to Bubbling Perfection:
Pop the dish into the oven Bake until the cheese is deeply golden and bubbling It will smell irresistible Let it stand 5 minutes to set before scooping
Serve and Garnish:
Scatter over fresh parsley for a pop of green and freshness just before you bring it to the table
A hearty Alfredo Butternut Squash Pasta Bake, filled with tender squash and rich sauce. Save
A hearty Alfredo Butternut Squash Pasta Bake, filled with tender squash and rich sauce. | tastybattle.com

My absolute favorite detail is the way the roasted squash gets soft and sweet and then melds into the creamy Alfredo I once made this for a family birthday and we ate the leftovers cold the next morning straight from the dish That is how good it is

Storage Tips

Cool the pasta bake completely before covering Store in the fridge for up to three days Leftovers reheat beautifully in the oven or microwave with a tiny splash of milk to keep the sauce creamy

Ingredient Substitutions

Fusilli or rotini work just as well as penne or rigatoni For dairy free needs swap the milk and cream for plant-based alternatives and use a vegan cheese blend If you do not have butternut squash try diced pumpkin or sweet potato

Serving Suggestions

Pair with a crisp salad dressed simply and a hunk of rustic bread This bake is filling enough to be the star of the table Serve with a bright white wine or sparkling water with lemon for a real treat

Cultural and Seasonal Context

Butternut squash has long been a cool weather staple Alfredo is a beloved Italian-American twist Best in autumn or winter when squash is at its sweetest but honestly I make it year round when I crave that warmth

Seasonal Adaptations

Add wilted spinach or kale for a greener finish Dot in sun-dried tomatoes for summery brightness Switch in roasted mushrooms once mushrooms are in their autumn prime

Success Stories

A friend made this for a family with a new baby It was the first meal they ate together at the kitchen table and they still ask for the recipe I love hearing how this bake turns regular nights into special ones and how kids devour the squash without complaint

Freezer Meal Conversion

You can assemble this dish right up to the baking stage Cover well and freeze for up to two months Bake straight from frozen with an extra fifteen minutes covered and finish uncovered until bubbling and golden

Close-up of warm Alfredo Butternut Squash Pasta Bake, perfect comfort food for dinner. Save
Close-up of warm Alfredo Butternut Squash Pasta Bake, perfect comfort food for dinner. | tastybattle.com

Serve this pasta bake hot and garnish with plenty of fresh parsley. It always disappears fast at my table so make a double batch if you want leftovers.

Recipe Questions

Can I use a different type of pasta?

Yes, substitute penne with rigatoni, fusilli, or any short pasta shape for a similar result.

Is it possible to make this dish ahead of time?

Prepare the bake in advance, refrigerate, and simply reheat or bake just before serving for convenience.

How can I add more vegetables?

Sautéed mushrooms or cooked spinach can be mixed in for extra flavor and nutrition.

What can I do to lighten up the sauce?

Use half-and-half or a lower-fat milk instead of heavy cream to make a lighter sauce.

How do I achieve a golden, bubbling cheese topping?

Bake uncovered and sprinkle mozzarella and Parmesan evenly for the best golden, bubbly finish.

Are there allergen concerns with this dish?

This main contains dairy and wheat. Verify all ingredients if preparing for those with dietary restrictions.

Alfredo Butternut Squash Pasta

Comforting bake with creamy Alfredo, roasted squash, tender pasta, and golden cheese topping.

Prep duration
20 min
Cook duration
40 min
Complete duration
60 min
Created by Alex Ramirez


Skill level Easy

Heritage Italian-American

Output 4 Portions

Nutritional specifications Meat-free

Components

Pasta

01 10 oz penne or rigatoni pasta

Vegetables

01 1 medium butternut squash (about 1.75 lbs), peeled and cut into 1/2 in cubes
02 2 cloves garlic, minced
03 1 small yellow onion, finely chopped
04 1 tbsp olive oil

Alfredo Sauce

01 2 tbsp unsalted butter
02 2 tbsp all-purpose flour
03 1 2/3 cups whole milk
04 1/2 cup heavy cream
05 3/4 cup freshly grated Parmesan cheese
06 1/2 tsp salt
07 1/4 tsp black pepper
08 Pinch ground nutmeg

Topping

01 1 cup shredded mozzarella cheese
02 1/3 cup grated Parmesan cheese
03 2 tbsp chopped fresh parsley (optional)

Directions

Phase 01

Prepare baking dish: Preheat oven to 400°F (200°C) and lightly grease a 9 x 13 in baking dish.

Phase 02

Roast butternut squash: Toss butternut squash cubes with olive oil, salt, and pepper. Spread on a baking sheet and roast for 20 minutes, stirring halfway, until tender and lightly golden.

Phase 03

Cook pasta: Boil pasta in a large pot of salted water for 2 minutes less than package instructions. Drain and set aside.

Phase 04

Sauté aromatics: In a large saucepan over medium heat, melt butter. Add onion and cook for 3 to 4 minutes until softened. Add garlic and cook for 1 minute.

Phase 05

Prepare sauce base: Stir in flour and cook for 1 minute. Gradually whisk in milk and heavy cream, stirring constantly until the sauce thickens, about 4 to 5 minutes.

Phase 06

Finish Alfredo sauce: Remove saucepan from heat and stir in grated Parmesan, salt, pepper, and nutmeg until smooth and creamy.

Phase 07

Combine components: In a large mixing bowl, gently fold together cooked pasta, roasted butternut squash, and Alfredo sauce until evenly coated.

Phase 08

Assemble and top: Transfer mixture to prepared baking dish. Sprinkle mozzarella and additional Parmesan evenly over the top.

Phase 09

Bake and finish: Bake for 20 minutes, or until the cheese topping is golden and bubbling. Allow to rest for 5 minutes. Garnish with chopped fresh parsley before serving if desired.

Necessary tools

  • Large saucepan
  • Baking sheet
  • Large pot
  • Mixing bowl
  • Whisk
  • 9 x 13 in baking dish

Allergy details

Review each component for potential allergens and seek professional healthcare advice if uncertain.
  • Contains milk, butter, cream, multiple cheeses, and wheat ingredients including all-purpose flour and pasta.
  • Verify product labels if preparing for individuals with food allergies.

Nutrient breakdown (each portion)

These values are estimates only and shouldn't replace professional medical guidance.
  • Energy: 590
  • Fats: 25 g
  • Carbohydrates: 72 g
  • Proteins: 21 g